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Role of endothelium in the production of potyblasts (mononuclear wandering cells) in inflammation.
Respectively, during stolon retraction, the exopinacocytes should dedifferentiate to the state of amoeboid wandering cells by means of epithelial-mesenchymal transition.
Seyfried also proposes an uncommon theory of metastasis, in which wandering cells do not just break away from the primary tumor but are themselves either transformed macrophages or at least fusion cells made up of cancer cells and macrophages.