1 By definition cavernous hemangioma (CH) is an unencapsulated mass of dilated vascular channels
lined by endothelial cells and filled with RBCs.
Microscopy revealed anastomosing vascular channels
lined by atypical endothelial cells.
During fetal life, this vascular channel
causes the majority of blood to bypass the lungs (pulmonary circulation) of the fetus.
Histologically, cavernous hemangiomas appear as closely packed, dilated vascular channels
lined with a layer of flattened endothelial cells.
The biopsy specimen exhibited dilated vascular channels
with flattened endothelium that were mostly blood-filled--findings that were consistent with a vascular malformation containing lymphatic and venous channels (figure 2).
9) Some investigators further speculate that PT may be related to a lymphatic or vascular abnormality, based on the observation of the frequent lymphatic or vascular proliferation and dilation of vascular channels
and its unusual distribution within the stroma of PT.
There are congested vascular channels
in the dermal region.
All biopsies showed hemorrhage associated with atypical epithelioid and spindle cells, forming anastomosing vascular channels
, distributed along and within lymphatics and arteries.
In addition, the lesion was confined to the vascular lumen and consisted of a complex network of vascular channels
Final pathology of the right-sided lesion revealed mostly dilated vascular channels
with unremarkable overlying respiratory mucosa, consistent with a hemangioma (figure 3).
7) Grade I, low-grade, angiosarcomas are characterized by anastomosing vascular channels
containing pleomorphic round to oval proliferating endothelial cells with hyperchromatic nuclei (Figure 2).
Angiosarcoma is a primary mesenchymal tumour of endothelial cell origin with anastomosing vascular channels