Embryonic stem cells (ESCs) are cells isolated from the inner cell mass of a blastocysts (5- to 7-day-old embryo) and represent the only truly totipotent cell
OAR proceeds by "switching on" a gene or genes in the somatic donor cell nucleus that are expressed in pluripotent cells, but are "off" in totipotent cells
. The procedure produces pluripotent cells that are not derived from totipotent cells
, so they can never be said to have had the "finality" present in the very early embryo; that is, they have never had the potential to produce all the necessary tissues in the coordinated fashion definitive of embryos.
In contrast, harvesting stem cells, or any other research activity that would imply the destruction of the embryo or any totipotent cell
, was prohibited by the EschG.
However, cells collected to develop into stem cell lines for research are not the totipotent cells
found in the very beginning of development.
fusion of an egg and a sperm leads to a diploid totipotent cell
. A totipotent cell
is capable of turning into all cell types of an organism including the placental cells.
Germ cell tumour is a totipotent cell
, Undergoing variable differentiation into tissue component that represents derivatives of ectoderm, mesoderm, endoderm.
ANT, as described above with the combination of alterations in Cdx2 and Nanog, would not only preclude the establishment of the gene expression pattern of a totipotent cell
, but would also initiate the transformation of the somatic cell nucleus directly toward the epigenetic configuration of a pluripotent stem cell.
Since a totipotent cell
can develop into a complete organism, it could be considered an embryo.
Stem Cells based on their cell potency and differentiation are divided into unipotent cells, multipotent cells, pluripotent cells and totipotent cells
These cases demonstrate that most living plant cells are truly totipotent cells
, being capable of redifferentiating into any other plant cell type (see Lev-Yadun, 2003).
 The tumor is thought to originate from the totipotent cells
in the basal layer; however, there is insufficient information about BSCC as a result of the low number of cases.