Bilateral topical administration
of an NMBA for mydriasis induction was previously described only in a study that involved common buzzards and little owls.
This involves the topical administration
of a photosensitizing compound, followed by selective irradiation of the lesion with visible light.
PH-10 is an aqueous hydrogel formulation of Rose Bengal disodium for topical administration
to the skin, and is being studied for the treatment of cutaneous skin disorders, specifically psoriasis and atopic dermatitis.
The FDA Breakthrough Therapy Designation for SD-101 in EB patents was based on clinical data from a previously conducted open-label Phase II study with topical administration
of SD-101 in children with either Simplex, Recessive Dystrophic (RDEB), or Junctional EB.
Novasorb(R), is designed to improve topical administration
of ophthalmic medicines.
The patents cover both inhalation and topical administration
of alpha 1-antitrypsin for the treatment of pulmonary and dermatological diseases.
DermaPrep, which recently obtained European CE Mark approval, offers a novel topical administration
method not only for DermaVir, but for a variety of liquid formulations and vaccines as well," Dr Lori added.
It is our hope and expectation that Cellgate's transporter technology will safely and efficaciously expand ISA247's use to the 65% of patients with mild psoriasis and supplement those with moderate to severe psoriasis via topical administration
These studies included immunocompetent adults and HIV-positive patients and examined the topical administration
of the combination of five percent acyclovir and one percent hydrocortisone in a unique cream vehicle (Xerese[TM]/Xerclear[R]) for the treatment of recurrent herpes simplex labialis.
The application of an occlusive knee bandage with either heat or exercise following topical administration
showed faster initial but lower overall plasma exposure of ketoprofen relative to non-occluded topical administration
with no heat or exercise.
The main purpose of this trial is to establish the local safety and efficacy of CTA018 following topical administration
Pending IND approval, Moores UCSD Cancer Center intends to proceed with a Phase 1, single-center, prospective, open-label study assessing topical administration
of Nupen in 10 healthy adult subjects.