Pannekoek, "Kinetic characterization of
tissue-type plasminogen activator (t-PA) and t-PA deletion mutants," Thrombosis and Haemostasis, vol.
Hart, "In vitro oxidative damage to
tissue-type plasminogen activator: a selective modification of the biological functions," Cardiovascular Research, vol.
Soluble expression and purification of human
tissue-type plasminogen activator protease domain.
Those who presented within 3 hours of symptom onset had to be ineligible for, or refractory to recombinant
tissue-type plasminogen activator (rTPA) therapy to be enrolled.
He agreed that recombinant
tissue-type plasminogen activator (rt-PA), urokinase, and streptokinase are not believed to cross to an embryo or fetus in amounts sufficient to cause hemorrhage.
Recombinant
tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset.
Specifically, the researchers have examined the effects of alcohol and polyphenols on the expression of proteins and pathways that can lead to increased fibrinolysis (including,
tissue-type plasminogen activator, t-PA; urokinase-type plasminogen activator, u-PA and plasminogen activator inhibitor type 1, PAI-1).
When a person is rushed to an emergency room with a heart attack or stroke, doctors often prescribe immediate infusions of
tissue-type plasminogen activator (tPA).
Australian researchers, seeking to compare DSPA with
tissue-type plasminogen activator, injected 16 mice with a neurotoxin and with either DSPA or
tissue-type plasminogen activator (Stroke 34[2]:537-43, 2003).
Collen, "Identification of a conformationally distinct form of plasminogen activator inhibitor-1, acting as a noninhibitory substrate for
tissue-type plasminogen activator," Journal of Biological Chemistry, vol.
Thrombolytic therapy-low-dose and prolonged infusion of
tissue-type plasminogen activator (tPA) (25 mg in six hours)--was initiated as previously described (5).