The rapid onset and recovery of the neurological symptoms coupled with presence of internal and external ophthalmoplegia and characteristic nerve conduction studies helps us to differentiate tick paralysis from other conditions causing neuromuscular paralysis.
Tick paralysis in children: electrophysiology and possibility of misdiagnosis.
The peak time for tick paralysis is tick mating season: April through June.
In the United States, tick paralysis occurs most often in the Pacific Northwest and Rocky Mountain states.
The exact mechanism of neurotoxic paralysis in Dermacentor tick paralysis is unknown, but neuro-electrophysiological studies suggest that sodium flux across distal motor axonal membranes is blocked at the nodes of Ranvier, leaving neuromuscular transmission unimpeded.
Grattan-Smith PJ, Morris JG, Johnston HM, et al Clinical and neurophysiological features of tick paralysis.
is thought to be caused by a toxin secreted in tick saliva during feeding that reduces motor neuron action potentials and the action of acetylcholine, depending on the species of tick (1,3).
Editorial Note: Tick paralysis
occurs worldwide and is caused by the introduction of a neurotoxin elaborated into humans during attachment of and feeding by the female of several tick species.
is caused by a neurotoxin produced by egg-engorged female ticks, who transmit the toxin from their salivary glands to the dog during feeding.