As with botulism, bound
tetanus toxin cannot be reversed.
Another three jars contained an orange color mix which "when stored in an anaerobic environment creates
tetanus toxin, which once contracted, attacks the central nervous system and causes death," a member of the service risk management at BCIJ explained to HuffPost.
Tetanus toxin binds at neuromuscular junction and enters motor nerve by endocytes.
J
Tetanus toxin light chain holds the HEXXH zinc protease consensus motif and acts as a toxic part of toxin and zinc-dependent endopeptidase(5,6).
Clostridium tetani was isolated from 2 patients;
tetanus toxin was detected in serum from 1 and also from another patient.
Carbachol stimulation of receptor coupled phospholipase C in the TRPC3 expressing cells increased TRPC3 surface expression, but was attenuated in cells where VAMP2 protein was degraded via
tetanus toxin. These cells also showed decreased [CA.sup.2+] influx upon stimulation.
The nucleic acid molecule can encode an epitope of interest and/or an antigen of interest and/or a nucleic acid molecule that stimulates and/or modulates an immunological response and/or stimulates and/or modulates expression, e.g., transcription and/or translation, such as transcription and/or translation of an endogenous and/or exogenous nucleic acid molecule; e.g., one or more of influenza hemagglutinin, influenza nuclear protein,
tetanus toxin C-fragment, anthrax protective antigen, HIV gp 120, human carcinoembryonic antigen, and/or a therapeutic, an immunomodulatory gene, such as co-stimulatory gene and/or a cytokine gene.
To test transplanted cells' ability to function immunologically, his group injected
tetanus toxin into mice transplanted with blood cells from human adults previously immunized for tetanus.
The disease is caused by
tetanus toxin produced by Clostridium Tetani and is diagnosed entirely on the basis of the clinical findings.
