(5) We defined a "perikaryon" as a large cell with extensive, finely granular amphophilic cytoplasm, and a large nucleus with dispersed chromatin with or without a prominent nucleolus, and with or without accompanying sustentacular cells
. We tallied as perikarya objects that clearly partially represented perikarya.
Our study indicated that lower dose of onion seeds extract (200 mg/kg BW) could increase the number of sustentacular cells
. Therefore, the increase in sustentacular cells
might be one reason for the significant improvement of spermatogenesis by onion seeds extract.
S100 highlights the peripheral sustentacular cells
(Figure 2, F).
BMMSCs were cultured for two weeks in the adult Sustentacular cell
condition medium that was obtained after 24 h and 48 h.
The control negative group (200x; H&E) has normal cyto-architecture, reveal interstitial tissues (IT) and seminiferous tubules (ST) with sustentacular cells
and the normal developing germ cells: spermatogonia (Sp), spermatocytes I (SPI), spermatids (Spt), spermatozoa (Spz) with flagellum.
A, Centrally located chief cells with abundant eosinophilic cytoplasm surrounded by peripherally located slender, spindled sustentacular cells
forming a nested (Zellballen) pattern separated by a prominent vascular network.
Immunohistochemistry revealed diffuse expression of chromogranin A, synaptophysin and neuron specific enolase, and S100 staining in sustentacular cells
; Ki-67 was <5%.
These cells form a "zellballen" pattern of nests separated by vascular stroma and spindle-shaped sustentacular cells
The researchers have been working with adult olfactory stem cells that give rise to the neurons that sense odors and other cells, such as sustentacular cells
, that support the neurons.
S100 immunohistochemistry highlighted sustentacular cells
, consistent with a paraganglioma.
Histological sections revealed typical morphological features of PCC predominantly characterized by nests of plump tumor cells with abundant basophilic granular cytoplasm surrounded by sustentacular cells
S100 highlights sustentacular cells
. Adrenal cortical carcinoma (ACC) also needs to be considered, especially when there is involvement of the adrenal gland.