cell

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cell

an independent team of operatives who work together in a CELLULAR MANUFACTURING production environment.
References in periodicals archive ?
Gabrilovich, "The nature of myeloid-derived suppressor cells in the tumor microenvironment," Trends in Immunology, vol.
Gabrilovich, "The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity," European Journal of Immunology, vol.
As previously mentioned, there are published data describing neutrophils as suppressor cells. Some mechanisms have been identified and their relevance has been described, such as downregulation of the TCR [zeta] chain due to the consumption of L-arginine, which is important for T-cell proliferation (25).
Abbreviations Cell Populations APCs: Antigen-presenting cells CTLs: Cytotoxic T cells DCs: Dendritic cells MCs: Mast cells MDSCs: Myeloid-derived suppressor cells NKs: Natural killer cells PMN: Polymorphonuclear cells TAMs: Tumor-associated macrophages Th: T helper cells Tregs: Regulatory T cells EMT: Epithelial-mesenchymal transition.
Avigan, "Myeloidderived suppressor cells as effectors of immune suppression in cancer," International Journal of Cancer, vol.
In melanoma and colon cancer, TEXs could curb peripheral [CD14.sup.+] monocytes differentiating into DC cells, while inducing them into myeloid-derived suppressor cells (MDSCs) [20].
The primary endpoint of the trial will be overall response rate, which will be assessed in the overall population as well as in subsets of patients with different baseline levels of myeloid derived suppressor cells. Opdivo is approved for use by the FDA as a single agent in patients with locally advanced or metastatic urothelial cancer who have progressed or recurred following treatment with platinum-based chemotherapy or who have disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.
The therapy blocks suppressor cells and activates anti-tumour effector cells, transforming the microenvironment of the tumour.
The other markers used in the previous study were as follows: IgG and CTL responses to the vaccinated peptides, frequency of circulating myeloid-derived suppressor cells (MDSCs), plasma levels of serum amyloid A (SAA), C-reactive protein (CRP), and interleukin-6 (IL-6).
Conrad and his colleagues examined two groups of mice that involve myeloid derived suppressor cells, where the first group was infected with a rodent intestinal helminth to simulate a strong allergic response.