(B) Neoplasm composed of polyhedral cells with ample eosinophilic cytoplasm that is often vacuolated, with some cells presenting "spider cell" appearance.
The described "spider cells" were also observed in other reports (OMAR, 1969; TANIMOTO & OHTSUKI, 1995; KOLLY et al., 2004; JACOBSEN et al., 2010) and, this aspect occur after routine processing, which causes the loss of glycogen (TANIMOTO & OHTSUKI, 1995; RADI & METZ, 2009).
In the case presented here, considering the morphologic features, the lesion should also be differentiated from adult rhabdomyoma, which is composed of large cells with abundant eosinophilic or clear cytoplasm and scattered spider cells
. (11) Typical cytoplasmic glycogen can be demonstrated on periodic acid-Schiff stain, whereas the muscle characteristics of the cells can be confirmed by strong positive reaction for desmin, muscle-specific actin, and myoglobin.