* Correlation of IgG fluorescence in Tzanck smear as compared to skin biopsy
However, in our patient, the only deep ulcer observed was due to skin biopsy
(in right lower extremity).
Bone marrow, spleen, lymph nodes, or liver biopsies were not performed; however, dermal lymphohistiocytic infiltration with phagocytosed erythrocytes were seen in skin biopsy
plays a pivotal role in diagnostic armamentarium of a dermatologist and is a common procedure to be practised.
Caption: Figure 4: Skin biopsy
: intact epidermis on one side and lesion on the other.
Caption: Figure 1: Hematoxylin and eosin stained skin biopsy
showing epidermis and dermis with periadnexal and interstitial inflammatory cell infiltrate (red arrows), magnification = 5 x.
Excisional skin biopsy
was performed on the ulcerated lesion over the clavicular region and a punch biopsy was taken from a lesion on the back.
On histopathologic evaluation, the skin biopsy
specimen revealed leukocytoclastic vasculitis (Figure 1b).
In medical applications this has great potential because you can always get a skin biopsy
. Cells can be grown in large numbers and reprogrammed, without genetic modification.
(10) Of note, these samples were multibacillary and did not match skin lesions biopsies of patients submitted to skin biopsy
showed granulomatous inflammation caused by Mycobacterium intracellulare.
Caption: Figure 1: Obtaining a skin biopsy
containing a sweat gland and staining of sudomotor nerve fibers.