Expression of ion channels during differentiation of a human skeletal muscle cell
This study was to deal with the potential regulation of HIF-1a and skeletal muscle cell
proliferation, differentiation, and carbohydrate metabolism through transcriptome analysis in skeletal muscle conditional HIF-1a -KO mice.
Although satellite cells exhibit some multipotential differentiation capabilities , their primary differentiation fate is skeletal muscle cells
in normal muscle regeneration.
Hood, "Calcium-dependent regulation of cytochrome c gene expression in skeletal muscle cells
. Identification of a protein kinase c-dependent pathway," The Journal of Biological Chemistry, vol.
Effect of 4-HIL derivatives on GLUT4 translocation to cell surface in L-6 GLUT4myc skeletal muscle cell
In addition, stimulation of 4-1BB enhances inflammatory cytokines in TNF[alpha]-pretreated skeletal muscle cells
. Conversely, disruption of the 4-1BB/4-1BBL interaction reduces inflammatory responses in cocultured muscle cells/macrophages and in the skeletal muscle of obese mice fed a high-fat diet.
By analyzing human development, the researchers found a fetal skeletal muscle cell
that is extraordinarily regenerative.
A previous report from our laboratory demonstrated the intracellular actions of IGFBP-6 in the cytoplasm and nucleus of skeletal muscle cell
line RD cells which is likely an IGF-independent actions of IGFBP-6 .
Blachnio-Zabielska et al., "Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell
models: a mechanistic insight," PLoS One, vol.
Nevertheless, the term myokine has also been employed to describe a protein that is synthesized by skeletal muscle tissue, rather than by the skeletal muscle cell
. The initial characterization of a candidate myokine is frequently the detection of the gene expression in skeletal muscle tissue by mRNA expression or immunodetection of protein lysates.
The exercise-stimulation increases in the translocation of GLUT4 to the skeletal muscle cell
membrane occur in people who are healthy and in patients with T2DM (14).
When the contractile units begin toshorten in a skeletal muscle cell
, says Warshaw, each individual unit works against the contraction of its neighbor, so while the cell is able to shorten quickly, only the units at the cell ends are directly pulling on the cell and the resultant net force equals that of only one unit.