Jayaprakash et al., "Different profile of mRNA expression in sinoatrial
node from streptozotocin-induced diabetic rat," PLoS One, vol.
Caption: Figure 1: Telemetry recording from the time of syncopal event in our patient demonstrating sinoatrial
arrest and a 26-second pause.
Cardiovascular cocaine toxicity can be related to its pathophysiological effects on the sinoatrial
node, myocardium, and vasculature, including the coronary district.
The combination of rapid diastolic depolarization and shortage of the action potential of the sinoatrial
cells causes this effect .
To create biological pacemakers, one approach is to coax stem cells to become specialized cardiac pacemaker cells that are normally found within the sinoatrial
node of the heart.
This, in turn, causes increased heart rate and increased velocity of electrical conduction from the sinoatrial
(SA) to the AV node (Smith, 2014).
Electrocardiographic features of arrhythmic syncope * Non-sustained VT * Bifascicular block (LBBB or RBBB combined with left anterior or left posterior fascicular block) or other intraventricular conduction delay with QRS >120 ms * Sinus bradycardia (<50 bpm or sinoatrial
block in absence of negative chronotropic medications or physical training) * Pre-excited QRS complex * Prolonged or shortened QT interval * RBBB pattern with ST elevation in V1--V3 (Brugada pattern) * Negative T waves in the right praecordial leads, epsilon waves, and ventricular late potentials suggestive of ARVC ARVC = arrhythmogenic right ventricular cardiomyopathy; LBBB = left bundle branch block; RBBB = right bundle branch block; VT = ventricular tachycardia.
(6) The former situation can be seen during periods of sinus arrhythmia, sinus bradycardia, sinus arrest, or sinoatrial
exit block, and the latter with accelerated junctional rhythm and ventricular tachycardia.
The [alpha]-2 adrenergic agonists can cause bradycardia, decreased cardiac output, sinoatrial
blocks, first and second grade of atrio-ventricular block, atrio-ventricular dissociation, and marked sinus arrhythmias.
A reduction in HRV indicates an inability or attenuation in the autonomic nervous system's or sinoatrial
node's responsiveness to change.
Ivabradine is an oral drug that inhibits the If current ("funny" current) in the sinoatrial
node, the body's cardiac pacemaker.
This interval is characterized as the time necessary for the electrical impulse to be conducted from the sinoatrial
node (SAN) to the ventricles.