Ser

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Related to serine: Amino acids, threonine

Ser

An obsolete Indian unit of dry volume equivalent to one liter.
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To amplify the major portion of Spbtry1, the following degenerate primers were designed according to the amino acid residues flanking the His and Ser of the serine proteases SP-F and SP-R active site (Table 1) (Waniek et al.
Doxycycline led to a significant drop in serine protease activity by week 8, compared with baseline and with the placebo group.
The company has created a proprietary platform, based on technology developed at The Scripps Research Institute by Professors Ben Cravatt and Dale Boger, that specifically targets serine hydrolases with selective small molecules.
They said CBR-5884 has a particular enzyme called as 3-phosphoglycerate dehydrogenase, that is accountable for the initial step in serine biosynthesis.
Three synthetic substrates were assessed: N-benzoyl-DL-arginine-p-nitroanilide hydrochloride (BAp-NA) for trypsin-like serine proteases; N-succinyl-AlaAla-Ala-p-nitroanilide (SAAApNa) for elastase-like serine proteases; and Ala-Ala-Phe-p-nitroanilide (AAPpNa) for chymotrypsin-like serine proteases.
Regarding mechanism of action of NF-B its phosphorylation is necessary at Serine 276 site of p65subunit[4].
However, the mechanisms of serine protease and pH increase underlying these abnormalities have been described only recently and may not be as widely understood.
Scientists at the Max Planck Institute of Neurobiology in Martinsried have now discovered a new serine protease: neutrophil serine protease 4, or NSP4.
Peripheral neurons may be particularly sensitive to the HSAN1 mutation possibly because peripheral neurons have low levels of serine synthase activities, resulting in a high alanine-to-serine ratio.
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis.
There is a lot of potential for a significant impact if a therapy targeting the serine pathway were found to be effective," lead researcher Dr Richard Possemato told BBC.
Glycine is a nonessential amino acid synthesized in vivo from the amino acid serine.
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