CEO Allen Eaves said the company expects to develop products from this license that enable scientists to have access to sensory cells
in sufficient quantities needed to develop therapeutic cures for hearing and balance disorders.
This expression pattern suggests that Pax2 might have diverse roles in sensory cell
development within the cochlea.
Many electrophysiological parameters such as velocity of conduction, modality, and adaptation rate serves to differentiate large number of functional types of sensory cell
bodies, but it is still not clear how these are related to basic histological types.
They are richly endowed with sensory cells
, which may be significantly different in each of the major groups of gastropods (Haszprunar 1988, Beesley et al.
Each of these facets overlays a discrete ocellus unit averaging 100 [micro]m in length and constituted by a central sensory cell
surrounded by usually five pigment cells (Fig.
In transverse sections, each of the leaf and the leaflet can be divided into two areas: the basal area consists mainly of two types of large goblet cells, and the apical area that contains a mixture of supporting cells, sensory cells
and four types of mucus-secreting cells.
1B) Neuronal cell types within the apical disc are clearly visible, as are the paraxial nerve cords (AN) that merge with the nerve nodule (NN) near the pyriform organ (Fig 1B) All sensory cell
types and neuronal cell bodies in the apical disc (AD) are labeled by acetylated [alpha]-tubulin (Fig.
These fibers possibly belonged to developing sensory cell
bodies, which might be absent or very low in GLU content along the surface of the tail.
Each sensory cell
appears to display copies of a single olfactory receptor.
Chia and Koss (1984) concur on this point, but also note that more than one sensory cell
type is present, thus the AG probably has more than one sensory function.
Interaction of mechano- and chemosensory signals within the same sensory cell
Like the RFamide-positive neuron population as a whole, all significant changes in the RFamide-positive ganglion cell, RFamide-positive sensory cell
, and RFamide-positive unclassifiable neuron numbers between stages were increases (Fig.