Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination
Kano, Nigeria, provides another example of the effectiveness of ring vaccination
, one that public health officials could emulate to contain smallpox in the event of a bioterrorist release today.
involves swift vaccination of people who were in very close contact with the smallpox victim," Kohn said.
is still considered the most crucial strategy for curtailing transmission of the smallpox virus.
was used to eradicate wild cases of smallpox.
One of the key tools in the plan is a "ring vaccination
," a technique that was successful in eradicating the disease in 1978.
We would first try to contain an epidemic by isolating the patients and vaccinating only those who've been in contact with them, the strategy called "ring vaccination
." Eventually, the entire nation might need to be immunized, but only if an outbreak were spiraling out of control.
INSTITUTE QUARANTINENorth Horr, Balesa, Demo, Shuur and Maikona are also affected.Following the crisis, the veterinary department plans to enhance surveillance, institute ring vaccination
to control disease spread, increase public awareness, institute quarantine of livestock, restrict home slaughter, and close livestock markets.
In March 2015, a phase 3 ring vaccination
trial of a recombinant vesicular stomatitis virus-Zaire Ebola virus vaccine began in Guinea (2).
On April 1, 2015, WHO and partners began an Ebola ring vaccination
trial in Guinea to evaluate the efficacy of a recombinant, replication-competent vesicular stomatitis virus-based vaccine expressing a surface glycoprotein of Ebola virus (rVSV-ZEBOV) (5).
After 10 years, the overall reduction is estimated at 19% - compared with 34% for a cull and 40% for a cull with ring vaccination