MEN2A is the most prevalent, with a mean age of onset of disease (first prototypic
tumor) of 37.5 years.
Our data show that prions from a prototypic
rigid-loop species (deer) can transmit to a flexible-loop species (mice).
HMGB1 acts as a DNA chaperone, chromosome guardian, autophagy sustainer, and protector from apoptotic cell death inside of the cell, on the other hand, it's the prototypic
damage associated molecular pattern molecule outside the cell (Rui et al., 2014).
Subacute cutaneous lupus erythematosus: 25-year evolution of a prototypic
subset (subphenotype) of lupus erythematosus defined by characteristic cutaneous, pathological, immunological, and genetic findings.
Offermann and his colleagues (1994) developed a measure with eight dimensions of ILTs grouped under the labels of prototypic
(dedication, sensitivity, attractiveness, intelligence, charisma, and strength) and anti-prototypic (Masculinity and Tyranny).
Emerging evidence suggests that TFH cell-derived lymphomas are part of a single spectrum of disease, with AITL being considered as "prototypic
" TFH cell neoplasm .
Remarkably, these efforts lead to the development of two mutation-specific small molecule therapies for Cystic Fibrosis, a prototypic
feat that would be much welcomed for other disease-associated ABC proteins .
(1,2) Currently, three distinct genotypes of B19V have been identified: (i) genotype 1, with subtypes 1a (the prototypic
virus) and 1b; (ii) genotype 2 (A6 and LaLi strains); and (iii) genotype 3, with subtypes 3a (V9 strain) and 3b (D91.1 strain).
SLE is a prototypic
autoimmune disease with complex pathogenesis.[sup], Adult SLE patients can produce a series of autoantibodies against nuclear and cytoplasmic antigens.[sup], It is well known that anti-Sm autoantibody, which was first described by Tan and Kunkel,[sup] is considered as a highly specific marker for adult SLE.
To illustrate these findings, we offer excerpts of prototypic
Furthermore, a FRET-based HPV6/11 RT-PCR (40), enabling reliable detection and differentiation of 25.3, 42.9, and 43.4 DNA copies of HPV11 and prototypic
and non-prototypic HPV6 genomic variants, respectively, was additionally used to determine the causal agents of condylomata acuminata.
 Moreover, there is an important cross-talk between the tissue NO signaling and XOR, a prototypic
superoxide-producing enzyme, as XO-derived superoxide can react with excess NO to form peroxynitrite, which has adverse effects on tissue homeostasis.