Previous attempts to correlate portal hypertension
or the risk of variceal bleeding with the serum levels of direct biomarkers such as laminin, type III procollagen, and hyaluronic acid did not provide affordable results [48-50].
The association of PHE and the presence of esophageal varices and/or portal hypertension
gastropathy was documented by both Goulas et al.
Thus, GA-MRI may identify patients with improving liver function (i.e., regression of liver fibrosis and portal hypertension
) and those with persistent liver damage despite SVR to IFN-free therapies.
Wu et al., "Role of 2-dimensional Doppler echo-cardiography in screening portopulmonary hypertension in portal hypertension
patients," Hepatobiliary & Pancreatic Diseases International, vol.
In our subject, the SAAG was 1.9 consistent with portal hypertension
, and together with a total protein of 3.1 mg/dL both are suggestive for a posthepatic etiology of the ascites .
As detailed above, embolization of the feeding vessels does not treat the underlying portal hypertension
. Thus, this approach is of limited value in isolation in patients who are good candidates for TIPS procedure.
Several case reports have discussed bleeding from vaginal varicosities with etiologies rooted in portal hypertension
This study provides new information in that the most common cause of UGIB was portal hypertension
instead of peptic ulcer.
The use of MRE of the liver in assessment of portal hypertension
has been explored in animal models ; however studies in humans are limited to the detection of clinical manifestations of portal hypertension
, such as the development of esophageal varices .
Fallowfield, "Noninvasive evaluation of portal hypertension
: emerging tools and techniques," International Journal of Hepatology, vol.
A contrasted CT scan of the thorax, abdomen, and pelvis showed a liver of normal size and density with multiple retrocrural, retroperitoneal, mesenteric, and left iliac metastatic lymphadenopathy which caused extrinsic compression of the portal vein along with splenic vein partial thrombosis with left-sided portal hypertension
and perigastric and perisplenic collateral neovascularization (Figure 2).
Since then, the diagnostic criteria for HPS have been modified (Table 1) to include oxygen impairment, evidence of pulmonary vascular dilation, liver disease, and portal hypertension