Platinum

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Platinum

A rare and valuable metal. Platinum is used in jewelry and electronics. Platinum is traded as a commodity on various security exchanges. Platinum is volatile like other commodities, but generally maintains a relatively high price.

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Chan, "Human leukocyte antigen class i expression is an independent prognostic factor in advanced ovarian cancer resistant to first-line platinum chemotherapy," British Journal of Cancer, vol.

HLA-G expression is an independent predictor for improved survival in high grade ovarian carcinomas

Is it time to discontinue using high-dose chemotherapy for salvage of patients with advanced germ-cell tumors failing first-line platinum chemotherapy? Ann Oncol 2006;17:349-50http://dx.doi.org/10.1093/annonc/mdj036.

Consolidative high-dose chemotherapy after conventional-dose chemotherapy as first salvage treatment for male patients with metastatic germ cell tumours

Women who possess the biomarker identified by the Yale Cancer Center team - a variant of the well-known KRAS oncogene - are three times more resistant to standard platinum chemotherapy than women without the variant.

Tiny genetic variation can predict outcome of ovarian cancer treatment

Fennec has a license agreement with Oregon Health and Science University (OHSU) for exclusive worldwide license rights to intellectual property directed to STS and its use for chemoprotection, including the prevention of ototoxicity induced by platinum chemotherapy, in humans.

Fennec Provides Business Update and Announces Second Quarter 2019 Financial Results

Merck announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the National Medical Products Administration in combination with pemetrexed and platinum chemotherapy for the first-line treatment of patients with metastatic nonsquamous non-small cell lung cancer, with no EGFR or ALK genomic tumor aberrations.

Merck's KEYTRUDA approved in China for treatment of NSCLC

Javelin Ovarian 200 is a multicentre and randomised trial designed to assess the efficacy and safety of avelumab alone or in combination with PLD against PLD alone in 566 women with ovarian cancer that is resistant or refractory to platinum chemotherapy.

Pfizer and Merck announce that avelumab ovarian cancer drug fails to improve overall survival in phase III trial

They excluded studies that did not include a platinum chemotherapy drug and those that used only fish extracts such as only EPA or only DHA.

Does fish oil prevent chemotherapy from working?

The standard first-line chemotherapies, such as paclitaxel, gemcitabine, docetaxel, or vinorelbine, is usually used in combination with the platinum chemotherapy compound, and the treatment has become the main adjuvant treatment for various cancers, including NSCLC, bladder cancer and pancreatic cancer.

Expression levels of ERCC1 and RRM1 mRNA and clinical outcome of advanced non-small cell lung cancer

KEYTRUDA, in combination with pemetrexed and platinum chemotherapy, is indicated for the first-line treatment of patients with metastatic nonsquamous non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations.

European Medicines Agency Adopts Positive Opinion for Merck's KEYTRUDA in Combination with Inlyta as First-Line Treatment for Advanced Renal Cell Carcinoma

Eli Lilly (LLY) announced that the FDA has granted approval for a new indication for ALIMTA in combination with KEYTRUDA, developed and marketed by Merck (MRK), and platinum chemotherapy for the first-line treatment of patients with metastatic nonsquamous non-small cell lung cancer, or NSCLC, with no EGFR or ALK genomic tumor aberrations.

Eli Lilly says FDA granted approval for new indication for ALIMTA/KEYTRUDA combo

The European Commission has granted approval to US-based Merck for its anti-PD-1 therapy Keytruda (pembrolizumab) in combination with pemetrexed (ALIMTA) and platinum chemotherapy intended for treating metastatic nonsquamous non-small cell lung cancer, it was reported on Tuesday.