This is a systemic rather than local treatment for repair of the underlying pathophysiology of photoaged skin
. For years, skin treatments for cutaneous photoaging have been painful, involving application of caustic acids, or the use of dermabrasion, lasers or intense light, all of which often require prolonged wound healing.
studied the combined use of oral and topical green tea extract in 40 women with moderate photoaged skin
to evaluate the clinical and histological characteristics.
Light emitting diodes are amongst the latest advancement in visible light spectrum for photoaged skin
. This device is thought to act by targeted stimulation of fibroblastic mitochondrial metabolic activity and, thereby, raising the pH, activating cyclic adenosine monophosphate (cAMP), and increasing DNA/RNA synthesis., concomitant upregulation of procollagen and downregulation of matrix metalloproteinase.7
In fact, numerous companies developing cosmeceuticals base their effectiveness claims on the fact that their formulations contain vitamins proven in laboratories to modify cellular processes thought to contribute to the appearance of photoaged skin
. As dermatologists, we can help our patients navigate this maze of marketing claims by sharing scientific data on the known efficacy of vitamins in skin care products."
The effect of an abrasive agent on photoaged skin
in comparison with topical tretinoin.
Specifically, the presentations cited that silybin has properties to improve and suppress wrinkles, inhibit the skin aging and improve the photoaged skin
Indeed, when he analyzed the monthly cost of the various topical therapies used by acne patients in his own practice, he determined that tazarotene cream 0.1% (marketed by Allergan Skin Care as Tazorac for acne and psoriasis and Avage for photoaged skin
) costs an average of slightly more than $15.
When applied to photoaged skin
that is rough and sallow, Retin-A can reverse the thinning of outer skin layers, reduce fibrous build-up in lower skin layers and help reconstruct the collagen network that supports the skin.