"The combination of the tissue deformation and the strain on the boundary of the optic cup
generates a hinge that further pushes the bending cells," said Okuda, "leading to the cup-like structure.
Mototsugu 2011 Assembled Eiraku neuroectodermal epithelium tissue and nonretinal neuroectodermal epithelium in three-dimensional culture and cocultured to induce of optic cup
. Xue-Jun 2008 Cultured Li neuroepithelial cells to generate motoneurons and then coculture of motoneurons and myocytes.
Mahapatra, "Glaucoma detection using entropy sampling and ensemble learning for automatic optic cup
and disc segmentation," Computerized Medical Imaging and Graphics, vol.
Masayo Takahashi, an ophthalmologist on Sasai's team, has already started transferring sheets of retina from lab-grown optic cups
into blind mice in hopes of restoring their vision, and she plans to do the same with monkeys by the year end.
Image thresholding was applied using an Interval Type-II fuzzy entropy based thresholding scheme with Differential Evolution on the localized image to detect the intensity of the optic cup
In 2-D fundus image the optic disc region was divided into two regions the centre bright region called optic cup
and the outer peripheral region called the neuroretinal rim.
Ectoderm-specific active [beta]-catenin expression disrupts optic cup
patterning resulting in a lack of cornea, conjunctiva, and eyelid development .
Citation: "Self-Formation of Optic Cups
and Storable Stratified Neural Retina from Human ESCs;" Tokushige Nakano et al.; Cell Stem Cell, Volume 10, Issue 6, 771-785, 14 June 2012, DOI: 10.1016/ j.stem.2012.05.009
The mechanistic basis for the formation of the optic cup
, with its complex two-walled structure, has been a longstanding question in embryology.
The same antibodies also react with a substance in the optic cups
of the optic cushion of A.
Size of the neuroretinal rim and optic cup
and their correlations with ocular and general parameters in adult Chinese: the Beijing eye study, Br J Ophthalmol 2007;91:1616-1619.
Held annually, the two-day event, which is sponsored by Specsavers, sees optometry undergraduates from each of the nine UK universities that offer the degree gather to compete for the coveted Optic Cup