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Using the method described by Noordzij et al, (7) we conducted a study to examine the viability, host response, and volume retention characteristics of drilled human septal cartilage slurry injected into a nude mouse model.
Scientists later discover that the nude mouse lacks a functioning thymus, a gland that plays a key role in immune development.
The flux or permeability coefficient, which is the indicator for total absorption of dermal delivery due to the use of nude mouse skin, was the greatest for QM, followed by the glycosides and quercetin.
We found that As-transformed HBECs display highly migratory and invasive potentials, and the nude mouse xenograft tumors resulting from subcutaneous inoculation of As-transformed HBECs were capable of invading into surrounding fat tissues and forming tubelike structures.