cell

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cell

an independent team of operatives who work together in a CELLULAR MANUFACTURING production environment.
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Langlais et al., "Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival," BMC Cancer, vol.
Cereblon: A Protein Crucial to the Multiple Functions of Immunomodulatory Drugs as well as Cell Metabolism and Disease Generation
Dendritic cell vaccination, an example of this approach, works by induction of idiotype-specific T- and B-cell response that can stimulate the body's own immune system to fight and eradicate myeloma cells following administration of idiotype-protein pulsed dendritic cells.
Post-autologous (ASCT) stem cell transplant therapy in multiple myeloma
Salmon, "A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival," Cancer, vol.
CD38 ligation in peripheral blood mononuclear cells of myeloma patients induces release of protumorigenic IL-6 and impaired secretion of IFN[gamma] cytokines and proliferation
Hideshima et al., "Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model," Cancer Research, vol.
Mammalian target of rapamycin inhibitors induce tumor cell apoptosis in vivo primarily by inhibiting VEGF expression and angiogenesis
Keywords: Enhanced green fluorescent protein, Flow cytometry, Monoclonal antibody, Myeloma cell lines, Transfection
Optimization of gene transfection in murine myeloma cell lines using different transfection reagents
Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu.
p38 mitogen-activated protein kinase and hematologic malignancies
Inhibition of Aurora A has been shown to induce cell death in preclinical multiple myeloma cell lines.
EntreMed's ENMD-2076 Demonstrates Antitumor Activity in Multiple Myeloma Model
DMA(V) exerted differential antiproliferative and cytotoxic activity against leukemia and multiple myeloma cells, with no significant effect on normal progenitor cells (Duzkale et al.
Intracellular calcium disturbances induced by arsenic and its methylated derivatives in relation to genomic damage and apoptosis induction
Thus, an inhibition of osteoblast proliferation by myeloma cells may not necessarily be accompanied by a simultaneously suppressed matrix mineralization.
Biochemical markers of bone formation in patients with plasma cell dyscrasias and benign osteoporosis
Menarini Silicon Biosystems, the pioneer of liquid biopsy technology, announced that it will introduce a new semi-automated assay workflow utilizing the CELLSEARCH and DEPArrayTM platforms to enumerate and characterize circulating multiple myeloma cells (CMMC) from peripheral blood samples.
Italy : Menarini Silicon Biosystems Develops New Assay Workflow for Circulating Multiple Myeloma Cells
Furthermore, most, if not all, human myeloma cell lines which survive in laboratory cell culture have TP53 deficiency, further suggesting its importance in extramedullary disease.
The genetic architecture of multiple myeloma
DARZALEX binds to CD38 and inhibits tumor cell growth causing myeloma cell death.
Janssen submits BLA to US FDA seeking approval of new DARZALEX (daratumumab) subcutaneous formulation for multiple myeloma

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