In conclusion, COAPT trial showed that in patients with moderate-to-severe or severe secondary
mitral regurgitation with heart failure who remained symptomatic despite the use of maximal doses of GDMT, transcatheter mitral valve repair (MitraClip) resulted in a lower rate of hospitalization for heart failure, lower mortality, and better quality of life and functional capacity within 24 months of follow-up than medical therapy alone.
It treats
mitral regurgitation by allowing the valve to close more completely, helping to restore normal blood flow through the heart.
Mitral regurgitation and other co-factors (such as age, female sex,
mitral regurgitation, and smoking) are found to be independent factors associated with WMH (Table 3).
Relation of frequency and severity of
mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure.
It was defined as post procedure
mitral regurgitation of grade [greater than or equal to] +3 or +4 quantified by color Doppler transthoracic echocardiography (Acuson CV 70 Siemens) using MR jet to left atrial (LA) area ratio.
Anatomy of the mitral valvular complex and its implications for transcatheter interventions for
mitral regurgitation. J Am Coll Cardiol 2010;56:617-26.
In a study by Radha Krishnan, out of 100 cases of acquired valvular heart disease the maximum brunt is borne by mitral valve and was involved in 56%, 27% had isolated mitral stenosis, 14% cases had isolated
mitral regurgitation, 17% cases had mitral stenosis and
mitral regurgitation, 13% cases were aortic stenosis with aortic regurgitation and 26% with multivalvular heart disease.
Caption: Figure 5: (a, b, c) Bilateral coronary artery aneurysms and moderate
mitral regurgitation on the first month after the surgery.
Transesophageal echocardiogram also revealed EF 35% with left ventricular global hypokinesis and moderate-severe
mitral regurgitation. Infectious endocarditis was ruled out with serial blood cultures, and no vegetations were found on imaging.
Through this study, published in PLOS Medicine, the researchers determined that a link exists between high blood pressure in your younger years and a much greater risk of
mitral regurgitation as you age.
It found that higher blood pressure in early life was associated with a significantly greater future risk of
mitral regurgitation, a condition which makes the heart less efficient at pumping blood around the body and in severe cases can lead to heart failure.
The findings showed that higher blood pressure in early life was associated with a significantly greater future risk of
mitral regurgitation - a condition which makes the heart less efficient at pumping blood around the body, and in severe cases can lead to heart failure.
