Following gastric bypass surgery in morbidly obese diabetic patients, MMP-9 and NOM levels dropped, along with the expression of six asthma-related genes including the key factors, interleukin 4, LIGHT,
lymphotoxin beta and interleukin 33 in parallel with weight loss and improvements in the status of their diabetes.
Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity.
IL-6,
lymphotoxin, RANKL (receptor activator of nuclear factor kappa B ligand), and intracellular kinases].
Th1 cells secrete IL-2, IFN-[gamma], and
lymphotoxin, and are primarily associated with macrophage activation and delayed-type hypersensitivity.
Selmaj K, Raine CS, Cannella B, Brosnan CF: Identification of
lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.
Enbrel binds to
lymphotoxin and TNF-alpha, blocking its interaction with cell surface TNF receptors, thus preventing synovial inflammation.
Remsima (infliximab) is a chimeric human-murine monoclonal antibody that binds with high affinity to both soluble and transmembrane forms of TNF alpha but not to
lymphotoxin [eth] (TNF beta).
About Inflectra Inflectra (infliximab) is a chimeric humanCaemurine monoclonal antibody that binds with high affinity to both soluble and transmembrane forms of TNF[eth] but not to
lymphotoxin [eth] (TNF[eth]).
To measure the effects of microbes and immunity, the researchers compared normal mice with mice that have a genetic defect that renders them unable to produce
lymphotoxin, a molecule that helps to regulate interactions between the immune system and bacteria in the bowel.
He was homozygous for 4 gene polymorphisms associated with higher susceptibility or severity of severe sepsis or both and ARDS: CD14,
lymphotoxin alpha, TNF-alpha, IRAK-1, and IL-6 (6-9).
Structural deficiencies in granuloma formation in TNF gene targeted mice underlie the heightened susceptibility to aerosol Mvcobacterium tuberculosis infection, which is not compensated for by
lymphotoxin.
The interaction of the polymorphisms in transporter of antigen peptides (TAP) and
lymphotoxin alpha (LT-alpha) genes and atopic diseases in the Czech population.
