cell

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cell

an independent team of operatives who work together in a CELLULAR MANUFACTURING production environment.
References in periodicals archive ?
The idea behind the liver cell injections was to "seed" this liver with normal cells containing the missing enzyme, thereby avoiding transplantation.
The launch comes following Lonza's purchase of US liver cell specialist Triangle Research Laboratories last year.
However, gene replacement therapy with AAV is not ideal for treating genetic diseases of the liver that manifest as newborns since the non-integrating genome is lost as developing liver cells proliferate.
Cytonet says its liver cell therapy has the potential to stabilize ammonia levels through infusion of healthy liver cells, potentially increasing the length of time children can safely wait until they can undergo a liver transplant.
This meant that bombarding the liver with drugs that cause cells to commit cell suicide, or apoptosis, would destroy healthy liver cells while allowing infected cells to escape unscathed.
And liver cells don't survive in typical cell cultures, confounding scientists who want to grow them in the lab.
The ground-breaking research on the liver cell therapy is currently being developed by the Cytonet in partnership with the University Hospital of Heidelberg.
The Fa2N-4 cell line has also been engineered to function as a proxy for normal human liver cells for use in performing drug toxicity assays.
Equally important, I consider HepaLife's PICM-19H cell research of particular significance since it directly addresses the widely-held scientific opinion that the greatest hindrance in development of a therapeutically effective artificial liver device has been the lack of an appropriately defined liver cell line, able to provide the functions of an intact liver," Soheili concludes.
According to the company, the results suggested the AAV5 vector from uniQure's bacculovirus production platform is safe by inducing liver cell transfection in AIP patients without liver enzyme perturbations at the tested dose levels.