chain

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Related to light chain disease: kappa light chain, LCDD

chain

A unit of measurement formerly used in surveying and still seen in deeds with old property descriptions.One chain equals 66 feet.

References in periodicals archive ?
We, as investigators of the TOURMALINE-MM1 trial, felt it was vital to conduct a comprehensive real world evaluation of this combination that included some of the most common patient types in the relapsed/refractory multiple myeloma setting, such as older patients, patients with moderate renal impairment, light chain disease, and high risk cytogenetics.
Sensitive nephelometric assays for free [kappa] and [lambda] chains are more effective in detecting conditions where only monoclonal light chains are produced (light chain disease or amyloidosis) or where there is minimal secretion of intact immunoglobulins (non-secretory or oligosecretory multiple myeloma).
A male:female ratio between 2:1and 3:1 for IgD myeloma has been reported (4, 5, 7), compared with a 1:1 ratio seen in IgG myeloma or light chain disease. In addition to a small or absent M-spike on serum protein electrophoresis, laboratory findings that differentiate IgD myeloma from the more common IgG and IgA myelomas include the presence of a [lambda] light chain predominance, as seen in our case, and higher rates of Bence Jones proteinuria (5, 7).