the leader in scalable, high performance cell loading systems, will host case study discussions with industry experts demonstrating how the MaxCyte[R] STX[TM] Scalable Transfection System improves transfection of cells with ion channels
for cell-based assays for drug discovery screening.
Not surprisingly, protons do not cross cell membranes; they must be transported across the membrane through special proteins like ion channels
Therefore, addressing impacts of the number of active ion channels
is important especially to uncover the role of specific ion channel
noise on neuronal spiking activity.
TetraGenetics' CEO, Doug Kahn said We chose to focus on ion channels
several years ago due to their importance in therapeutic drug discovery and the limited availability of high quality material required to launch effective programs.
TetraGenetics uses these recombinant proteins to discover and develop new drugs for ion channel
related autoimmune diseases and pain management.
We are delighted that this alliance with Icagen, and their expertise in ion channel
and transporter technologies, has the potential to put both companies in a position to help our customers increase their chances of successful IND filing.
are specialised proteins that are selectively permeable to particular ions.
The use of primary cells in conjunction with automated electrophysiology is essential to achieving higher physiological relevance for ion channel
proteins exist to allow charged ions like Na+ to pass through the non-polar environment of the cell membrane.
to perform ion channel
screening for drug discovery research while providing an order of magnitude improvement in both throughput and cost effectiveness.
Could such ion channel
abnormalities contribute to MS?
Menthol, popularly known for its cooling effect, activates TRPM8--a coldactivated thermoTRP ion channel