Nevertheless, literature review revealed no cases of interstitial nephritis as renal manifestation in Sweet Syndrome (being only described mesangiocapillary glomerulonephritis), reinforcing the diagnosis of a
hypersensitivity reaction to AZA.
Diagnosis of sulfonamide
hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites.
The lack of laboratory tests to confirm the
hypersensitivity reaction was a weak point; however, the timing of symptoms and their relief following our treatment support the clinical diagnosis of sugammadex-induced hypersensitivity.
Hypersensitivity reactions to lyophilised ASV were seen among some of the cases and all of them recovered with intravenous hydrocortisone and antihistamine, with premedication proving to be helpful in reducing albeit preventing any
hypersensitivity reactions.
As the use of clopidogrel has proliferated,
hypersensitivity reactions have been increasingly recognized [7].
Furthermore, azathioprine has an inactive metabolite, methyl nitroimidazole, which may be responsible for the
hypersensitivity reactions due to the generation of a hapten during metabolism [4, 9, 11, 12].
Delayed-type reactions consist primarily of type IV reactions, which are T cell-mediated delayed-type drug
hypersensitivity reactions. These reactions usually take several days or even weeks to manifest following drug exposure.
Other associated factors include food additives, fungi, parasites, pneumotoxic substances, thermal stress, viral pneumonia, bacterial infection, irritating gases, and
hypersensitivity reactions (RAVIOLO et al., 2007b; DOSTER, 2010).
* the absence of a label warning about
hypersensitivity reactions associated with the PEG 40 castor oil;
Papular urticaria may be a
hypersensitivity reaction to another insect, and the urticarial lesions are usually on the exposed parts of extremities.
Sugar alcohols rarely cause
hypersensitivity reactions, although there have been reports of reactions to mannitol [1-4] and erythritol [5].
In this article we present a case of chlorhexidine-induced anaphylaxis during a surgical procedure where adequate diagnostic investigation was performed allowing the identification of the allergen that triggered the immediate
hypersensitivity reaction.