Viral hemorrhagic fever
caused by Congo virus and dengue virus is endemic in Pakistan.
Dengue Fever and Dengue Hemorrhagic Fever
. In: Kliegman, Behrman Jenson and Stanton.
The epidemiology of tick-borne Crimean-Congo hemorrhagic fever
in Asia, Europe, and Africa.
An outbreak of Crimean-Congo hemorrhagic fever
in western Anatolia, Turkey.
Examination of the specific clinical symptoms and laboratory findings of Crimean-Congo hemorrhagic fever
. J Vector Borne Dis 2016;53(2):162-167.
[2.] Ozkurt Z, Kiki I, Erol S, Erdem F, Yilmaz N, Parlak M, Gundogdu M, Tasyaran MA Crimean-Congo hemorrhagic fever
in Eastern Turkey: clinical features, risk factors and efficacy of ribavirin therapy.
According to WHO, Dengue fever is a major health problem for Pakistan, Brazil and India.16 Dengue virus travels throughout the year with a peak incidence in the post monsoon period in Pakistan, but flood makes the situation worse.12 Seven dengue epidemics have been reported in last two decade from Pakistan.12,17 According to WHO, dengue fever was first reported from Punjab province of Pakistan in 1982, out of 174 suspected dengue cases 12 patients were declared positive.18 First epidemic of dengue hemorrhagic fever
of serotype DENV-1 and DENV-2 was reported in Karachi in 1994, followed by second episode of dengue epidemic with 800 registered cases of Baluchistan in 1997.18 In 2005 for the first time dengue endemic was reported with DENV-3 serotype.4
Treatment of Crimean-Congo hemorrhagic fever
. Antiviral Res, 2008; 78(1): 125-31.
By the WHO definition, a diagnosis of dengue hemorrhagic fever
requires the presence of fever for at least 2-7 days, hemorrhagic tendencies, thrombocytopenia, and evidence and signs of plasma leakage; dengue shock syndrome requires these, as well as evidence of circulatory failure, such as rapid and weak pulse, narrow pulse pressure, hypotension, and shock.
Zalgen is also a member of the Viral Hemorrhagic Fever
Consortium (VHFC), an academic and industry collaboration lead by Tulane University working to develop state-of-the-art diagnostic and immunotherapeutic products for biothreat agents and emerging pathogens.
The first sign of Crimean-Congo hemorrhagic fever
is a sudden onset of fever and other nonspecific symptoms including chills, severe headache, dizziness, photophobia, neck pain, myalgia and arthralgia.
Crimean-Congo hemorrhagic fever
, which is transmitted by ticks, is noteworthy because of its increasing prevalence and resulting mortality, particularly in recent years.