Wu said, aACoeWhen you have an infection, you need to mobilise the T cells,aACA[yen] adding, aACoeIn HIV infection, there is a profound depletion of helper T cells
in lymphoid tissues, such as those in the gut."
Insights into the role of follicular helper T cells
Zheng, "The development and function of follicular helper T cells
in immune responses," Cellular and Molecular Immunology, vol.9, no.5, pp.
"This could mean that helper T cells
, which are known to play a central role in the immune response, are critical in disease progression.
The number of infected helper T cells
in the bloodstream declined precipitously, to undetectable levels.
Angelucci et al., "A RING-type ubiquitin ligase family member required to repress follicular helper T cells
and autoimmunity," Nature, vol.
Antigen-presenting B cells and helper T cells
cooperatively mediate intravirionic antigenic competition between influenza A virus surface glycoproteins.
Normally, an encounter with a pathogenic virus or bacterium prompts these components, helper T cells
, to ooze proteins that alert other immune cells to work together to vanquish the intruders.
Both these and the B cells are made more potent by the adjuvant, stimulating helper T cells
which are required for initiation of immune responses and the development of immunological memory for long-term immune protection.