Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell
Serous cyst-adenocarcinoma was the commonest malignant tumour followed closely by endometrioid carcinoma and granulosa cell
Bilateral aggressive malignant granulosa cell
tumour with essentially different immunophenotypes in primary and metastatic lesions comprising predominantly sarcomatoid and fibrothecomatous patterns-looking for prognostic markers: A case report.
The differential diagnosis of cellular fibroma versus adult granulosa cell
tumor may be problematic, as some granulosa cell
tumors have a diffuse growth of cells that are somewhat spindled (so-called sarcomatoid granulosa cell
tumor), and only focal hints of epithelial differentiation may be a subtle clue to the diagnosis.
2000).The GDF9 secreted particularly from oocyte through folliculogenesis, it works synergistically with bone morphogenetic protein 15(BMP15) to enhance proliferation of granulosa cells
, increment in inhibin production and suppressing progesterone secretion induced by FSH (McNatty et al.
The developmental stages of the follicles were classified by the shape and number of layers of granulosa cells
The similar effects of daidzein, the phytoesrogen of soybean, on pig granulosa cell
culture have been reported (17).
It has previously been described that anethole stimulates granulosa cell
proliferation, and consequently follicular growth, during in vitro culture of isolated goat secondary follicles (10).
tumors have been described by ultrasound to vary in shape ranging from uniformly dense masses with one or many large fluid filled cyst like structures, however, this case refer to a single fluid filled Granulosa-Theca Cell Tumor (GTCT) that acutely doubles in size within 48 hours.
(1) Over 100 cases have been described, and although the pathogenesis is still controversial, there appears to be a relationship to hormonal factors including pregnancy, oral contraceptives, and rarely, granulosa cell
tumors of the ovary.
tumors (GCTs) represent only 5% of all ovarian cancers.