Glanders

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Glanders

A bacterial disease characterized by fever, coughing, nasal discharge and sometimes the development of nodules underneath the skin. It can cause death in days or months. Glanders is most common in horses and similar animals but can be contracted by humans. It was used in biological warfare during both world wars.
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In serodiagnosis, animals tested false-positives and false-negatives should be retested with a highly sensitive and specific test like immunoblot to avoid the loss of healthy animals and introduction of glanderous animals in healthy populations, respectively.