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Related to gene switch: Gene activation


1. See: Swap.

2. See: Roll forward.
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1. See swap.
2. To move funds out of one mutual fund and into another mutual fund. See also telephone switching.
Wall Street Words: An A to Z Guide to Investment Terms for Today's Investor by David L. Scott. Copyright © 2003 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved. All rights reserved.
References in periodicals archive ?
Ziopharm's Ad-RTS-hIL-12 plus veledimex construct is designed to express human interleukin 12, or hIL-12, under the control of an orally administered activator ligand, veledimex through a proprietary RheoSwitch therapeutic system gene switch. Data from this Phase 1 trial previously revealed a median overall survival, or mOS, of 12.7 months for patients treated with Ad-RTS-hIL-12 plus 20mg of veledimex at a mean follow-up time of 12.9 months as of May 4.
In most of the tissue samples of melanomas of all stages they found alterations in the telomerase gene switch, which the researchers clearly identified as typical consequences of sun exposure.
Using RTS technology, IL-12 expression is regulated using a controllable gene switch, which is activated by an orally-delivered small-molecule activator ligand (AL).
The patent is for a two gene system with one gene encoding a therapeutic protein and the other a "gene switch" which allows the therapy to be terminated.