Correlations with physiology: Total lung capacity (TLC), forced vital capacity (FVC), arterial blood oxygen saturation (Sa[O.sub.2]), diffusing capacity of the lung (DLco), forced expiratory volume
in 1 sec ([FEV.sub.1]), and change in [VCO.sub.2] with exercise ([DELTA][VCO.sub.2]) showed significant negative correlation with disease extent score, assessed on HRCT (Table III).
The means height, weight, forced expiratory volume
in 1 second, force vital capacity and peak expiratory flow rate were 137.3713.41cm, 30.448.56kg, 1.560.58, 1.720.50 and 3.661.10, respectively.
Spirometric measurements included, (i) FVC: Forced Vital Capacity; (ii) FEV1: Forced Expiratory Volume
in first second; and (iii) [FEV.sub.1]/FVC: ratio of Forced Expiratory Volume
in first second and Forced Vital Capacity.
RESULTS: Both the sexes responded similarly to the short-term practice of pranayama by showing significant increase in the lung parameters like the vital capacity, tidal volume, inspiratory reserve volume, expiratory reserve volume, forced expiratory volume
in first second and peak expiratory flow rate.
Overall, 96 children (74%) had moderate to severe asthma, and the mean lung function, based on forced expiratory volume
in 1 second, was 88.1 FE[V.sub.1].
Pulmonary function test results were as follows: forced vital capacity (FVC), 3.46 L (91%); forced expiratory volume
in 1 sec ([FEV.sub.1]), 2.31 L (74%); [FEV.sub.1]:FVC ratio, 67; total lung capacity, 5.27 L (95%); residual volume, 1.57 L (91%); diffusion capacity for carbon monoxide, 23.1 mL/mmHg/min (81%); and diffusion capacity for CO corrected for total lung capacity by single breath, 4.61 mL/mmHg/L (87%).
Results of lung function tests conducted 6 weeks after his first visit and at his second visit were the following: vital capacity, 3.271/3.341 (77%/74% of predicted vital capacity); and forced expiratory volume
, 1 s 2.811/2.891 (79%/77% of predicted forced expiratory volume
There was no difference in forced expiratory volume
in 1 second ([FEV.sub.1]) between groups.
TUESDAY, July 9, 2019 (HealthDay News) -- Use of a threshold of airflow obstruction of forced expiratory volume
in one second:forced vital capacity (FEV1:FVC) of 0.70 discriminates chronic obstructive pulmonary disease (COPD)-related hospitalization and mortality, according to a study published in the June 25 issue of the Journal of the American Medical Association.
AnaptysBio expects to report top-line efficacy and safety data, including improvement in Forced Expiratory Volume
in One Second, from its ongoing double-blinded, placebo-controlled severe eosinophilic asthma trial Phase 2a trial, where approximately 24 adult severe eosinophilic asthma patients are treated with a 300mg intravenous single dose of etokimab versus placebo, each in combination with inhaled corticosteroids and long-acting beta agonists as background therapy, in Q3.
The trial indicated a statistically significant improvement compared with dual combination therapies in six out of seven lung function primary endpoints based on forced expiratory volume
in one second assessments in patients with moderate to very severe chronic obstructive pulmonary disease.
Results: Pulmonary parameters such as tidal volume, vital capacity (VC), forced VC (FVC), forced expiratory volume
in first second ([FEV.sub.1]), maximum mid-expiratory flow rate, peak expiratory flow rate, and maximum voluntary ventilation were significantly reduced in scoliosis patients than controls, and they were inversely correlated with Cobb's angle.