It is recommended that
follicular cell carcinoma should be considered in the differential diagnosis of bone cyst in any patient with history of FTC even years after primary therapy.
Patel et al., "Encapsulated thyroid tumors of
follicular cell origin with high grade features (high mitotic rate/tumornecrosis): a clinicopathologic and molecular study," Human Pathology, vol.
The only case of HT with carcinoma showed evidence of increased lymphocytes on background, occasional thyroid
follicular cell cluster infiltrated by lymphocytes, and many scattered large atypical cells having large nuclei and intranuclear inclusion (Figures 4(a) and 4(b) arrow).
Normal ovarian architecture was defined as grade 0; mild oedema, mild
follicular cell degradation, mild vascular congestion, no haemorrhage and no leukocyte infiltration was grade 1; moderate oedema, moderate
follicular cell degradation, moderate vascular congestion, no haemorrhage and no leukocyte infiltration was grade 2; severe oedema, severe
follicular cell degradation, severe vascular congestion, minimal haemorrhage and minimal leukocyte infiltration as grade 3, and severe oedema, severe
follicular cell degradation, severe vascular congestion, haemorrhage and leukocyte infiltration as grade 4,12,13
Neutral glycoproteins were detected in the
follicular cells, pellucid zone, cortical alveoli and yolk globules of the six species studied due to the positive reaction to the PAS technique (Fig.
Follicular cell thyroid neoplasia: insights from genomics and The Cancer Genome Atlas research network.
Ghossein, "Problems and controversies in the histopathology of thyroid carcinomas of
follicular cell origin," Archives of Pathology & Laboratory Medicine, vol.
Using genomic, transcriptomic and proteomic assays on thyroid cell cultures (PC Cl 3 (PC) and
follicular cell line--derived from 18-month-old Fischer rats on Matrigel[R]--, they demonstrated that RET/ PTC3-RAS-BRAF axis acts synergistically to alter thyroid cells (in vitro and in vivo) into an invasive phenotype.
The concluding sections describe available treatments including hair transplant, hair ocloningo by
follicular cell implantation, autologous stem cell therapies, adjuvants such as prostheses and dermopigmentation, and cosmetology of cleansing and conditioning agents.
Malignant tumors of thyroid
follicular cell origin are categorized as well-differentiated thyroid carcinoma (WDTC), consisting the majority of papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma, poorly differentiated thyroid carcinoma (PDTC), and undifferentiated/anaplastic thyroid carcinoma (ATC).
There is the appearance of a continuous acidophilic layer, the vitelline membrane, which is surrounded by a layer of
follicular cells. The appearance of the vitelline membrane and
follicular cell layer assists the identification of this developmental stage, as reported for Hypostomus strigaticeps (Takahashi et al., 2008).