seal

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Related to fluorescein staining: blepharitis, cataract

seal

(1) An embossed impression created by a metal die pressed upon paper.A notary public seal, a corporate seal,or a government agency seal are all proof that the signature of that person is genuine and authorized,because they would not otherwise have access to the embosser to create the seal.(2) Originally,an impression made in wax upon a contract.It took the place of reciting consideration, having a signature, or having witnesses for the contract. Today, some statutes allow certain symbols,such as the initials “l.s.”to take the place of a seal,transforming a standard contract into one “under seal.”Where still recognized, contracts under seal may have a longer statute of limitations than others.

References in periodicals archive ?

The main outcome assessments (clinical endpoints) are improvement of corneal fluorescein staining (which is a measure of ocular surface inflammation), tear production, and dry eye symptom score.

Can-Fite BioPharma Announces the Initiation of Phase 3 in Dry Eye Syndrome

Lifitegrast did not meet the prespecified co-primary endpoint for the sign of inferior corneal staining score (change from baseline to Week 12) using fluorescein staining compared with placebo (p-value=0.

Shire Reports Top-Line Results on OPUS-2, a Phase 3 Study Investigating the Use of Lifitegrast (5.0% Ophthalmic Solution) in Adults With Dry Eye Disease

Reduction from baseline in exacerbation of superior corneal fluorescein staining in the chamber as compared to the placebo (p = 0.

RegeneRx Reports Positive Data with RGN-259 in Phase 2 Dry Eye Trial

Sodium fluorescein staining is essential to check for epithelial defects.

Corneal infiltrative events

In the moderate dry eye phase of the study, after six days of treatment, two concentrations of RGN-259 showed a statistically significant reduction in corneal fluorescein staining, a method used to determine the extent of damage to the cornea, which returned to near baseline (normal) levels.

RegeneRx Reports New Statistically Significant Data Confirming Repair of Corneal Damage in Dry Eye Model

The eye was congested, there was corneal fluorescein staining, and the corneal flap was partially detached and scrolled up (Fig.