Group II and III animals showed fatty changes
of grade 2+ while the fatty liver was graded as 3+ in Group I animals treated with low dose M.
Our study suggests that sodium arsenite caused disruption of hepatic architecture with fatty change
leading to increase in size of hepatic lobule in adult rats while collateral intervention with Lagenaria siceraria had protective effect on the hepatic architecture and subsequently on the size of hepatic lobule.
The result shows moderate fatty change
(MFC) with mild infiltrate of inflammatory cell (MIIC).
The histological alterations were mainly pyknosis, karyorrhexis, cytoplasmic vacuolation, necrosis, fatty changes
and hepatocyte atrophy.
Frequency of fatty change
in pulmonary and extra-pulmonary TB in various studies ranges from 20-44%.
The increase in relative liver weight in butter treated subgroups B1 and B2 animals was due to fatty change
, causing hypertrophy of hepatocytes due to accumulation of fat, as described by Kumar et al.19 who described similar findings in fatty change
jarbua, these alterations included vacuolated hepatocytes, fatty change
, adipocytes, vacuolated foci, inflammatory response, degeneration of hepatocytes, sinusoidal dilation and frank necrosis were noted in fish specimen collected from Al-Kumrah site as shown in figures (5a,b-6a,b).
Exposure of toxicants caused fatty change
, karyopyknosis, nuclear vacuolization and cytoplasmic collapse in liver of all experimental groups.
(41) However, a small sampling area can result in inaccurate assessment of the overall amount of fatty change
due to the heterogeneous distribution of fat.
The profound relevance of this evolutionary design to the pathogenesis of insulin-toxic states - obesity, fatty change
of the liver, diabetes, cardiovascular disorders, and others - is underscored.
Pathologist Dr David Scoones later carried out a post-mortem examination and gave the cause of death as fatty change
of the liver.
may be a manifestation of excessive fat transport to the liver or decrease in its removal from the liver.