(182,183) The thiol-functionalized silica intercepts MeHg and other metals trapped in
enterohepatic circulation, binding them and escorting them out of the intestines.
Enterohepatic circulation of BS is driven by several specific transport systems expressed predominantly in hepatocytes and biliary and intestinal epithelia (Figure 1).
Considering a theoretical abnormal reabsorption of bile acids of 94% in the
enterohepatic circulation, on the seventh day, the estimated cutoff retention value would be 10%.
Pharmacological studies have shown that EZE is readily absorbed in the small intestine and undergoes
enterohepatic circulation [45].
Medications that are poorly intrinsically absorbed and undergo
enterohepatic circulation are likely to be underabsorbed after a malabsorptive bariatric procedure.
in American alligators was 55 29 h which could be caused by the physiological feature of decreasing gut blood flow in rest.The possibility of
enterohepatic circulation of EF was indicated by the double peak-shaped curve of the plasma concentration-time data following p.o.
Its long half life is due to the storage in multiple organs, such as kidneys, lung, spleen, liver, brain, muscle and
enterohepatic circulation. Kruger G et.
It is also clear that many OCs undergo
enterohepatic circulation; that is, they move from tissues in which they are stored to the blood, are taken up by the liver, and enter the intestine in bile.
The toxicology and pharmacology literature suggests that inter-individual variations in gut microbiota may affect chemical metabolism via direct activation of chemicals, deplete metabolites needed for biotransformation, alter host biotransformation enzyme activities, change
enterohepatic circulation, alter bioavailability of environmental chemicals and/or antioxidants from food, or alter gut motility and barrier function.
It is well-absorbed from the gastrointestinal tract with a significant
enterohepatic circulation. The elimination half-life of DDS averages between 24 and 30 hours, with significant variability ranging between 14 and 83 hours (4).
Enterohepatic circulation and enteric recycling of isoflavones are important because they allow body tissues to be exposed to these phytochemicals for longer amounts of time following soy intake.
