Wang et al., "Enterochromaffin cell
and 5-hydroxytryptamine responses to the same infectious agent differ in Th1 and Th2 dominant environments," Gut, vol.
In mammals, the enterochromaffin cells
synthesize 90% of the 5-HT in the enteric nervous system and release 5-HT hormonally in response to mechanical or chemical stimulation (Erspamer.
Moreover, it has been reported that the expression of T lymphocytes, enterochromaffin cells
, and interleukin-1[beta] was increased in the lamina propria of the colons of patients with IBS (5-7).
Most AET are serotonin-producing enterochromaffin cell
tumors (Figure 1, c).
10 Gastric NETs originate from enterochromaffin cells
. They are an incidental finding on endoscopy and seen as multiple, small less than 1-2 cm sized polyps usually located in gastric fundus and body.
TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells
. Proc Natl Acad Sci USA 2009; 106: 3408-13.
By using immunohistochemistry and in situ hybridization, it has been found that ANF gene expression is localized in the rat gastric antrum in enterochromaffin cells
(EC cells) in the lower portion of the antropyloric glands (Gerbes et al, 1991; Gower et al., 2000, 2003).
Enteroendocrine cells: It has been accepted that for the first time, enterochromaffin cells
appear at the 11th week of development (43, 44).