4% with enteric-coated
aspirin, a nonsignificant difference.
Out of these 13 trials refer to investigations with enteric-coated
PO and three to PO formulations without galenic specification, the latter being presumably also enteric coated.
medications are formulated to resist gastric-juice action and thereby delay disintegration until reaching the intestine.
aspirin is involved, proper absorption may be delayed and the level of overdosage may not be apparent.
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(EC) and immediate-release omeprazole, in patients with previous cerebrovascular disease.
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Measurements indicating the presence of what has been thought to be aspirin resistance were evident only with enteric-coated
aspirin, not immediate-release aspirin, in a study of 400 healthy adults--a phenomenon the study's authors described as aspirin "pseudoresistance.
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tablets protect the active ingredient against degradation by gastric acid, and crushing these tablets will reduce the bioavailability of the drug.
It is said that enteric-coated
niacin is not quite as effective.
Patients using enteric-coated
aspirin also were more likely than others to show resistance.