Patients should look for 1-g fish oil capsules that each contain 180 mg of
eicosapentaenoic acid and 120 mg of docosahexaenoic acid.
Each 1-g capsule contains at least 900 mg ethyl esters of omega-3 fatty acids, mainly
eicosapentaenoic acid (465 mg) and docosahexaenoic acid (375 mg), according to label.
Fatty fish and fish oil contain 2 unusual kinds of fats, docosahexaenoic acid (DHA for short) and
eicosapentaenoic acid (EPA).
Until then, patients should look for 1-g fish oil capsules that each contain 180 mg of
eicosapentaenoic acid and 120 mg of docosahexaenoic acid.
In Asia, both, Australia/New Zealand and Japan have established a recommended dietary intake (RDI) level of
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) at levels of between 0.
The results of a double-blinded trial published in the Singapore Medical Journal show positive effects for the omega-3 fatty acid
eicosapentaenoic acid (EPA) in overweight type II diabetics.
Eicosapentaenoic acid (EPA) was strongly linked to lower risk of nonfatal heart attack, and docosapentaenoic acid (DPA) was most strongly associated with lower risk of dying from a stroke.
The publication titled,
Eicosapentaenoic Acid Ethyl Ester (AMR101) Therapy in Patients with Very High Triglyceride Levels, provides a peer-reviewed summary of the previously reported Phase III MARINE clinical trial data of Amarin's lead product candidate AMR101, in which a statistically significant reduction in triglyceride levels and other lipid parameters was observed without a statistically significant increase in LDL-cholesterol.
Patients with the greatest increase in
eicosapentaenoic acid concentration in the blood following fish oil supplementation had the greatest gains in muscle.
Fats in this group include alpha-linolenic acid (found in flax seeds and flax seed oil and, to a smaller extent, in canola oil and soy products), docosahexaenoic acid (DHA, found in fatty fish), and
eicosapentaenoic acid (EPA, also found in fatty fish).
Two omega-3 fatty acids in fish oil,
eicosapentaenoic acid and docosahexaenoic acid, exert anti-inflammatory effects by competitively inhibiting conversion of arachidonic acid to the proinflammatory eicosanoids prostaglandin E2 and leukotriene B4.
3 g per day of
eicosapentaenoic acid (EPA), 300 mg per day of alpha-lipoic acid (ALA), both treatments, or placebo for 10 weeks.
