Disposition

(redirected from drug disposition)
Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia.

Disposition

The sale of a security. See also: Close a position.
Farlex Financial Dictionary. © 2012 Farlex, Inc. All Rights Reserved
References in periodicals archive ?
Cutler, "The potential role of lysosomes in tissue distribution of weak bases," Biopharmaceutics and Drug Disposition, vol.
Paneitz et al., "Effect of levothyroxine administration on intestinal P-glycoprotein expression: Consequences for drug disposition," Clinical Pharmacology and Therapeutics, vol.
Grapefruit products also could affect drug disposition through effects on various drug transporters.
In addition to the pharmacological effects, previous in vitro studies suggested that catechins may have an impact on the drug disposition by modulating the activities of drug metabolizing enzymes and uptake or efflux transporters (Jodoin et al.
The book has forty-one chapters including topics such as pharmacy math, federal pharmacy law, compounding, sterile products, nuclear pharmacy, pharmacokinetics, drug metabolism, and drug disposition, biotechnology and pharmacogenomics, biostatistics, and immunization.
Future studies should address not just the toxic effects of chemotherapy during pregnancy but also the pharmacokinetics of cytotoxic agents in pregnant women, because the physiologic changes of pregnancy can greatly affect drug disposition, said Dr.
The transporters recommended for initial assessment generally Included those for which A clinical relevance to drug disposition has Been identified, namely, the efflux transporters P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP), and the uptake transporters OCT2, OAT1, OAT3, OATP1B1 and OATP1B3.
The chapter on Pharmacogenomics by the third contributor (Anahita Bhathena), is an excellent summary of where we are in a number of areas, and includes the pharmacokinetics of drug disposition and even tables of useful Web sites.
Busulfan PK studies have demonstrated wide intra- and interpatient variation in drug disposition, metabolism, and clearance.

Full browser ?