Immunohistochemically, tumour cells were strongly positive for dendritic cell
markers CD21 and CD23 (Figure-4 and 5).
Immunohistochemical markers assist in arriving at the diagnosis of FDCS if the appropriate immunohistochemical markers specific for follicular dendritic cell
differentiation/FDCS are applied.
One of these checkpoints is antigen presentation, which is accomplished primarily by mature dendritic cells
Over the past 10 years, the Medical Center Cologne has treated roughly 3,800 of patients with dendritic cell
therapy for conditions that included brain tumors, primary bone cancer and bone metastasis, breast cancer, colon cancer, liver metastasis of all kinds, cholangiocarcinomas, lung cancer, malignant melanoma, and prostate cancer.
This patent application includes intellectual property that offers a means of specifically inducing dendritic cells
to internally generate tumour antigens, a process expected to be more effective than exogenously administering antigens to dendritic cells
Efficient targeting of protein antigen to the dendritic cell
receptor DEC-205 in the steady state leads to antigen Presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance.
Interdigitating dendritic cell
sarcoma: a report of four cases and review of the literature.
The current first generation (non-automated) manufacturing is highly precise, and achieves a concentration of at least 80% or more dendritic cells
in the vaccines.
In addition, Argos has used its dendritic cell
expertise to develop two novel treatments (one an antibody, the other a soluble protein) for autoimmune disorders and transplantation.
New research reveals that it may also affect the immune system by altering how dendritic cells
respond to biochemical signals [EHP 114:1083-1091; Goth et al.
Follicular dendritic cell
dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility.
Cancer Vac is developing immunotherapies based on effective Dendritic Cell