For the first time, we reported a series of Iranian patients with blastic plasmacytoid dendritic cell
neoplasm and presented our current practice at Shiraz University of Medical Sciences.
(DCs) are the most powerful professional antigen-presenting cells, and responsible for antigen recognition and procession. They could initiate primary immune response and play an important role in host defense against pathogen infection and tumor progression.
The neoplastic cells in interdigitating dendritic cell
sarcoma may be spindled or epithelioid, and the epithelioid neoplastic cells may resemble those of histiocytic sarcoma.
Treatment with dendritic cells
is also often used when conventional therapies have not been successful.
Inflammatory pseudotumor-like follicular dendritic cell
tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association.
Brang et al., "Proliferating dendritic cell
progenitors in human blood," The Journal of Experimental Medicine, vol.
Follicular dendritic cell
sarcomas commonly occur in lymph nodes of cervical region but also in mediastinal and axillary lymph nodes [5, 7, 12].
Immunohistochemically, tumour cells were strongly positive for dendritic cell
markers CD21 and CD23 (Figure-4 and 5).
Liu, "Mouse and human dendritic cell
subtypes," Nature Reviews Immunology, vol.
First, we demonstrate and propose that the major proportion of endogenous SGPP-l is located in the nuclear compartment in murine- and human-differentiated dendritic cells
. Second, upon inflammatory stimuli, translocation of SGPP-l into the ER occurs and potentially contributes to S1P fate and sphingolipid rheostat in dendritic cell
The diagnosis is mainly provided by detection of [CD4.sup.+] [CD56.sup.+], [CD123.sup.high], [TCL-1.sup.+], and blood dendritic cell
antigen-2 (BDCA2)/[CD303.sup.+] Lin- blasts .
therapy has no side effects for me, except for a touch of flu, which means that the treatment is catching on.