agent

(redirected from cytotoxic agent)
Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia.
Related to cytotoxic agent: cytotoxic drugs, Cytotoxins

Agent

A party appointed to act on behalf of a principal entity or person. In context of project financing, refers to the bank in charge of administering the project financing.

Agent

A person who acts on behalf of an organization or another person. Agents have a fiduciary responsibility to act in the best interests of the principal. Common examples of agents include brokers and attorneys. See also: Agency theory, Agency problem, Agency costs.

agent

An individual or organization that acts on behalf of and is subject to the control of another party. For example, in executing an order to buy or sell a security, a broker is acting as a customer's agent.

Agent.

An agent is a person who acts on behalf of another person or institution in a transaction. For example, when you direct your stockbroker to buy or sell shares in your account, he or she is acting as your agent in the trade.

Agents work for either a set fee or a commission based on the size of the transaction and the type of product, or sometimes a combination of fee and commission.

Depending on the work a particular agent does, he or she may need to be certified, licensed, or registered by industry bodies or government regulators. For instance, insurance agents must be licensed in the state where they do business, and stockbrokers must pass licensing exams and be registered with NASD.

In a real estate transaction, a real estate agent represents the seller. That person may also be called a real estate broker or a Realtor if he or she is a member of the National Association of Realtors. A buyer may be represented by a buyer's agent.

agent

a person or company employed by another person or company (called the PRINCIPAL) for the purpose of arranging CONTRACTS between the principal and third parties. An agent generally has authority to act within broad limits in conducting business on behalf of his or her principal and has a basic duty to carry out the tasks involved with due skill and diligence.

An agent or broker acts as an intermediary in bringing together buyers and sellers of a good or service, receiving a flat or sliding scale commission or fee related to the nature and comprehensiveness of the work undertaken and/or value of the transaction involved. Agents and agencies are encountered in one way or another in most economic activities and play an important role in the smooth functioning of the market mechanism. A stockbroker, for example, acts on behalf of clients wishing to buy and sell financial securities; an estate agent acts as an intermediary between buyers and sellers of houses, offices, etc.; while an insurance broker negotiates insurance cover on behalf of clients with an insurance company. A recruitment agency performs the services of advertising for, interviewing and selecting employees on behalf of a company. In addition to the role of agents as market intermediaries, organizational theorists have paid particular attention to the internal relationship between the employees (‘agents’) and owners (‘principals’) of a company See PRINCIPAL-AGENT THEORY.

agent

a person or company employed by another person or company (called the principal) for the purpose of arranging CONTRACTS between the principal and third parties. An agent thus acts as an intermediary in bringing together buyers and sellers of a good or service, receiving a flat or sliding-scale commission, brokerage or fee related to the nature and comprehensiveness of the work undertaken and/or value of the transaction involved. Agents and agencies are encountered in one way or another in most economic activities and play an important role in the smooth functioning of the market mechanism. See PRINCIPAL-AGENT THEORY for discussion of ownership and control issues as they affect the running of companies. See ESTATE AGENT, INSURANCE BROKER, STOCKBROKER, DIVORCE OF OWNERSHIP FROM CONTROL.

agent

One who acts on behalf of a principal in an agency relationship. See agency for an extended discussion.

References in periodicals archive ?
Open HIPEC methods have the highest exposure risk to cytotoxic agents. In this technique, as the CRS is completed, the abdominal cavity is flushed with heated chemotherapy.
Guidelines for the safe handling of excreta contaminated by cytotoxic agents. American Journal of Hospital Pharmacy, 49(8), 1957-1958.
A total of 27 patients elected to receive a cytotoxic agent. Of these, 21 were started on 7.5 to 15 mg/wk of oral methotrexate for at least 6 months unless toxicity or a lack of response necessitated an earlier termination of treatment; the remaining six were started on oral cyclophosphamide at 100 mg twice a day.
The company also announced that it has been awarded a $350,000 grant from the Illinois Technology Challenge Grant Program to develop a manufacturing process for betulinic acid (BA), a melanoma-specific cytotoxic agent with a unique mode of action.
By binding to B cell-specific CD22 receptors, Besponsa is internalized, triggering the release of the cytotoxic agent that causes double-strand DNA breaks and apoptosis.
According to the company, inotuzumab ozogamicin is an investigational antibody-drug conjugate (ADC) comprised of a monoclonal antibody (mAb) targeting CD22, a cell surface antigen expressed on approximately 90% of B-cell malignancies, linked to a cytotoxic agent. When inotuzumab ozogamicin binds to the CD22 antigen on B-cells, it is internalized into the cell, where the cytotoxic agent calicheamicin is released to destroy the cell.
In the trial, Amphinex is used together with the cytotoxic agent bleomycin in cancer patients.
It then selectively delivers a potent bacterial cytotoxic agent called PE38 derived from Pseudomonas bacterium to destroy tumor cells while sparing healthy surrounding cells.
It then selectively delivers a potent cytotoxic agent called PE38 to destroy tumor cells while sparing healthy surrounding cells.
SGN-CD48A uses the company's latest ADC technology advancement, a PEGylated glucuronide linker that improves stability, reduces off-target uptake, and enables conjugation of more molecules of the microtubule-disrupting cytotoxic agent monomethyl auristatin E per antibody.
It targets the marker CD22, which is expressed in more than 90% of patients with B-cell ALL.1 By binding to B cell-specific CD22 receptors, BESPONSA is internalized, triggering the release of the cytotoxic agent that causes double-strand DNA breaks and apoptosis.
Besponsa is an investigational antibody-drug conjugate comprised of a monoclonal antibody targeting CD22, a cell surface antigen found on cancer cells in almost all B-ALL patients, linked to a cytotoxic agent.