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Related to creatinine clearance: Creatinine clearance test, Serum creatinine


The process of settling transactions. Most exchanges have one or more clearing houses, which are charged with matching orders together, ensuring that deliveries are made to the correct parties, and collecting margin money. Because so many trades take place on an exchange in a given day, clearing houses exist to process what each party owes or is owed in a central location so the fewest securities actually change hands. For example, suppose that a broker-dealer buys 1000 shares of a security and then, in a completely separate transaction, sells 700 of the same shares. At the end of the trading day, the clearing house would determine that the broker-dealer must only buy 300 shares as the other 700 belong to another party. Clearing houses receive a clearing fee in exchange for clearance services.


Clearance is the first half of the process that completes your order to buy or sell a security. During clearance, the details on both sides of the transaction are compared electronically to ensure that the order to buy and the order to sell correspond.

For example, in a stock transaction, the Committee on Uniform Securities Identification Procedures (CUSIP) number, the number of shares, and the price per share must match.

Next, transactions within each broker-dealer are netted down, or offset, by matching its clients' buy orders against sell orders from others of its clients or among a group of affiliated firms. Their records are then updated to reflect the new ownership and account balances.

Any unmatched orders are forwarded to the National Securities Clearing Corporation (NSCC), which instructs selling broker-dealers to provide the relevant securities and the buying broker-dealer to send the cash.

References in periodicals archive ?
GFR was measured as the mean of two creatinine clearances based on 24-hour urine collections and adjusted for body surface area.
In summary, correlation of fluid management with guided fluid therapy based on the use of bedside ultrasound to assess IVC variation and collapsibility indices may increase the rate of improvement in creatinine and creatinine clearance in patients with AKI.
Renal functions were assessed by the creatinine clearance estimated using the Cockcroft-Gault formula15 and based on creatinine clearance were stratified into three groups i.e.
Gault, "Prediction of creatinine clearance from serum creatinine," Nephron, vol.
Estimated creatinine clearance (eCrCl) rate was calculated by using Cockcroft--Gault formula [9]:
* People starting tenofovir or other potentially nephrotoxic drugs (see Table 3 on page 34 of this issue) should first undergo urinalysis and calculated creatinine clearance so that these parameters can be tracked after treatment begins.
Furthermore, creatinine clearance was increased in the diabetic rats compared to the control group, suggesting glomerular hyperfiltration.
(5,8-10) Exogenous urine/plasma creatinine clearance has been shown to be almost equal to urinary inulin clearance in dogs, which is the reference method for GFR determination and to the clearances of other tracers of GFR.
Clearance increased with increasing renal filtration as assessed by creatinine clearance and increased with increasing body weight, presumably representing non-filtration elimination.
Renal insufficiency (RI) was defined when: (a) creatinine increased two times above baseline; (b) creatinine was above 2 mg/dL; or (c) creatinine clearance was below 50 mL/min; or (d) association of these criteria.
Patients with a creatinine clearance >=60mL/min were given lenalidomide at 25mg once daily for 21 days every 28 days.
DGF was defined as the need for dialysis in the first week post-transplant, while slow graft function (SGF) was defined as serum creatinine >265 [mu]mol/L on day 5, without a need for dialysis.[sup.4] Creatinine clearance was calculated using the Cockcroft-Gault equation (for stable creatinine) or the Jeliffe equation[sup.5] for non-steady-state creatinine, such as one would expect in the first postoperative week.

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