(18.) Makadia HK, Siegel SJ, Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery
carrier, Polymers (Basel) 3(3), 1377-1397, 2011.
Summary: Objective of the study was to synthesize a chemically cross-linked poly(hydroxyethylmethacrylate-co-methacrylic acid) hydrogel [p(HEMA-co-MAA hydrogel)] for pH-responsive, controlled drug delivery
Controlled Drug Delivery
: The Role of Self-Assembling Multi-Task Excipients
We hypothesize that anisotropic lipid coatings can produce concentration-independent reduced burst release and prolonged controlled drug delivery
from reservoir to sink.
In this case, a synergistic effect of hyperthermia and controlled drug delivery
for a hybrid system composed by the combination of SBA-15, [Fe.sub.3][O.sub.4]] nanoparticles, and P(N-iPAAm) has occurred.
Chowdhury, "Kinetic modeling on drug release from controlled drug delivery
systems, "Acta Poloniae Pharmaceutica--Drug Research, vol.
Youan, "Impact of nanoscience and nanotechnology on controlled drug delivery
," Nanomedicine, vol.
To overcome this restriction and to increase the bioavailability of drugs several controlled drug delivery
systems with prolonged gastric residence times reported recently [1, 2].
The contributors compare new capabilities introduced by nanotechnology to traditional methods of release, target and controlled drug delivery
in the body.
Two major avenues to controlled drug delivery
are being pursued today.
The concept of controlled drug delivery
was first introduced as a part of pharmaceutical industry via Wurster technique in 1949 and experienced Coacervation (liquid encapsulation) from 1953, offering microencapsulation technology in 1960 as a milestone in this progress .