(17) In the seminal article, these invasive tumors were described as nests of stratified columnar cells
with peripheral palisading, variable amounts of intracytoplasmic mucin, and evident HPV infection-related features with apical mitotic figures and apoptotic bodies, similar to SMILE (Figure 3, A through F).
(b) The cyst wall lined by a folded, thin, regular parakeratinized epithelium without rete ridges, and the basal layer lined by palisaded columnar cells
with hyperchromatic nuclei (HE; original magnification: x12.5 (a) and x100 (b)).
PASH like changes is also incidentally detected with other breast lesions such as fibrocystic disease, fibroadenomas, columnar cell
lesions, lobular neoplasia and in situ and invasive ductal carcinoma.
Overexpression of estrogen receptors in columnar cell
change and in unfolding breast lobules.
Elias et al found that the relative risk of finding mild to moderate dysplasia in Papanicolaou smears containing endocervical columnar cells
was 2.2 and that the relative risk of finding severe dysplasia or cancer was 4.4.
Fibrocystic changes comprised the largest number of the benign breast cases, closely followed by columnar cell
Among the benign lesions, fibroadenoma the second commonest benign lesion in our study was most commonly associated with usual hyperplasia of ductal type or usual ductal hyperplasia (UDH) constituting about 14 cases (36.8%), followed by fibrocystic lesion with usual ductal hyperplasia comprising 13 cases (34.2%), fibrocystic disease with columnar cell
change associated with usual ductal hyperplasia in 8 cases (21%), followed by sclerosing adenosis with UDH in 2 cases (5.2%), intraductal papilloma with UDH, and simple adenosis with usual lobular hyperplasia (ULH) comprised 1 case (2.6%) each (Table 6).
lesions of the breast: the missing link in breast cancer progression?: a morphological and molecular analysis.
The columnar cell
variant of PTC was first reported by Evans in 1986.
Rarely, the lining cells may take on a columnar cell
appearance that contains subnuclear vacuoles and shows reverse polarity, thus simulating piano keys.
Tubular carcinoma can also be an incidental finding in a biopsy performed for calcifications that are present in an adjacent benign proliferation, such as columnar cell
She underwent stereotactic needle core biopsy of the calcifications, which showed columnar cell
change with microcalcifications and ALH, as shown in Figure 1.