Expansion

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Related to clonal expansion: Clonal selection

Expansion

Phase of the business cycle as it climbs from a trough toward a peak.

Expansion

In a business cycle, a period of growth during which an economy moves from its trough to its peak. For example, if an economy dips to growth of -2.5% and then recovers to 3% growth, this period is called expansion. It is considered a normal and inevitable part of a business cycle following a recession or other contraction. Expansion is also called recovery.

References in periodicals archive ?

Treatment with compounds inducing differentiation of 3T3-L1 preadipocytes leads to mitotic clonal expansion prior to the expression of PPAR[gamma], a key adipogenic transcription factor.

Lignosulfonic acid promotes hypertrophy in 3T3-L1 cells without increasing lipid content and increases their 2-deoxyglucose uptake

Suppression of oncogenic signalling is necessary to prevent stimuli driving commitment to clonal expansion and differentiation from antagonizing the long-term maintenance of stem cell properties in the SCN.

The Leukemic Stem Cell Niche: Adaptation to "Hypoxia" versus Oncogene Addiction

A third emerging application of tracking clonal expansion is in the context of autoimmune diseases, where research is attempting to identify particular V - (D) - J recombinants associated with autoimmune diseases with the plan of monitoring their levels in response to therapeutic options.

Immune repertoire analysis is gaining interest as a clinical IMGS application

Sin et al., "Sulforaphane inhibits mitotic clonal expansion during adipogenesis through cell cycle arrest," Obesity, vol.

Ethanol extract of Alismatis rhizome inhibits adipocyte differentiation of OP9 cells

Hence, Stat3 status influenced survival of DNA-damaged KSCs, since the absence of Stat3 led to increased apoptosis of bulge region KSCs following treatment with DMBA ultimately leading to reduced number of mutated cells available for clonal expansion during tumor promotion [25].

Role of Stat3 in skin carcinogenesis: insights gained from relevant mouse models

(2010) Antigen-specific clonal expansion and cytolytic effector function of [CD8.sup.+]T lymphocytes depend on the transcription factor Bcl11b.

Role of the transcription factor Bcl11b in development and lymphomagenesis

Hypermutation combined with clonal expansion is an adaptive process known as affinity maturation (Berek & Ziegner, 1993).

Informative gene selection for clustering gene expression data using a hybrid GA/CSA

This suggests that MCPyV is involved in clonal expansion of the tumor.

Merkel cell virus may be target for treatment

Hampering of pyrimidine synthesis hinders T-cell clonal expansion (3).

Long term use of leflunomide as a cause of severe diarrhea? / Uzun sureli leflunomid kullanimi siddetli diyare nedeni olabilir mi?

They review research into the clonal expansion of a single, normal or mutated stem cell in order to bring new insights into both the biology of the gastrointestinal tract and tumorigenesis in the intestine.

Gut stem cells; multipotent, clonogenic, and the origin of gastrointestinal cancer

T-cell receptor gene rearrangement studies may suggest the presence of clonal expansion In some cases, however, these clonal expansions do not constitute a lymphoma [2,3].

Lymphoid and histiocytic proliferations in HIV-positive patients: problems in diagnosis

"In terms of lung cancer susceptibility, however, our observation that stem cell activation leads to clonal expansion after injury could, in the context of additional mutations, promote the development of cancerous or precancerous lesions from activated stem cells," Giangreco added.