DYNAMO2 is important for cytosolic GTP generation during the cell cycle
rather than for membrane remodeling, which is mediated by its homolog DYNAMO1.
Our unique BioINK platform preserves antigen and nucleic acid biomarkers while allowing simultaneous cell cycle
assessment on single cells captured using the Celsee Genesis microfluidic instrument.'
Combined analysis of DNA methylation and cell cycle
in cancer cells.
Wogonin might cause cell cycle
arrest via NF-?B/cyclin D1-mediated pathway and induce apoptosis by NF-?B/Bcl-2/caspase-mediated pathway.
PLK1 Inhibits Antitumor Immunity via the Cell Cycle
Notably, the amplitude of these changes in shape decreases over time during the cell cycle
. Moreover, this motion marks the first physical feature that systematically changes with the cell cycle
A prerequisite for activating the muscle gene program is progression into the cell cycle
, a process that is irreversibly inhibited in senescent cells.
Ki67 staining was also performed to show senescent cell in the cell cycle
phase as shown in Fig 3.
On the other hand, at low doses, DAC is incorporated into newly synthesized double-stranded DNA during the S phase of the cell cycle
without affecting elongation and induces cell cycle
arrest and cellular differentiation [22, 23].
Thus, we hypothesized that maternal sevoflurane exposure may disturb the differentiation and proliferation of neural progenitors by interfering the cell cycle
dynamics, which finally lead to learning deficits in offspring.
From the molecular biology point of view, the synergistic effect of nanomaterial's potential hazard to cell proliferation response can be monitored by investigating various gene and protein associated with cell cycle
checkpoint or circadian regulator , DNA damage surveillance, and DNA repair mechanism.
Our results indicated that the ethanol extract of root of Prunus persica can impair HepG2 cell viability and suppress cell growth through cell cycle
arrest and inhibit cell migration.